The 222 is a cool receiver because it can drive 1 HD and 1 SD TV with different programming simultaneously. It'll also downscale the HD content to SD. Perfect, right?!
Unfortunately when set to "dual user mode", the 2nd viewing instance will only respond to the UHF remote. Thus far, I've seen no solutions for Tivo to control UHF remote-controlled set-tops.
I just got my 222 the other day. I still have to tweak my setup (ie. the timer trick to prevent the screen-saver from interfering with recordings). Unfortunately, I think you'll have to use the 222 in single-user mode in order to get successful operation with your Tivo.
The good news is this isn't really any different than the functionality on your cable-box. Also, in single user mode, you can still get the second tuner's content in a PiP or PbP window.
The bad news is: I don't think there's a way to use the 222's SD output as a dedicated tuner for Tivo at this time.