You can plug the TiVo drive into one of the unused bays on your machine, but be aware that Windows will offer to 'initialize' it for you. If you allow that, the drive will become useless in the TiVo. Refuse that offer. I don't know what sort of SATA cable is in the TiVo you have, but one end can obviously connect to the drive. If the other end can plug into one of your motherboard's SATA connectors (plus you'll need a power connection), you can use it. A SATA cable is pretty much a SATA cable if the manufacturer used standard parts (not everyone does).