You can but it would be somewhat complicated because you'd have to make an identical copy of your drive using "dd", a Unix program. Most recent computers have several SATA connectors on the motherboard that would allow you to connect several hard drives at a time. If your optical drive is SATA you could use that connection as well. But if not you can buy an inexpensive SATA PCI card. Or if you're using a laptop, you should be able to utilize a USB/SATA adapter. All of the info on that can be found in the first post of this thread, Section V, number 17(b). BTW if you have a TiVo Series3, read the post to make sure the drive you have is one that will work (many do not due to a soft reboot issue). If you have a TiVo HD there shouldn't be a problem upgrading with a WD GP drive. If you've built computers, this will be a cakewalk. Even if you haven't, it's quite simple. Happy upgrading!